This can occur because of diet, genetic predisposition, or underexcretion of urate, the salts of uric acid. Examples are used only to help you translate the word or expression searched in various contexts. Quelques mots au hasard. [8] They may show signs of chronic gout such as bone erosion. When levels are between 415 and 530 μmol/l (7 and 8.9 mg/dl), the risk is 0.5% per year, while in those with a level greater than 535 μmol/l (9 mg/dL), the risk is 4.5% per year. [82], In the United States, gout is twice as likely in males of African descent than those of European descent. [27], Physical fitness, healthy weight, low-fat dairy products, and to a lesser extent, coffee and taking vitamin C, appear to decrease the risk of gout;[28][29][30][31] however, taking vitamin C supplements does not appear to have a significant effect in people who already have established gout. ○ Boggle. machuquer : mâchouiller. Carnivore mustélidé aquatique aux pattes palmées, mangeur de poissons. Chaque lettre qui apparaît descend ; il faut placer les lettres de telle manière que des mots se forment (gauche, droit, haut et bas) et que de la place soit libérée. [79] It is unclear whether dietary supplements have an effect in people with gout. LA fenêtre fournit des explications et des traductions contextuelles, c'est-à-dire sans obliger votre visiteur à quitter votre page web ! [107] Humans and other great apes do not have this ability; thus, gout is common. [15][107] Other animals with uricase include fish, amphibians and most non-primate mammals. Aphérèse de louloute, féminin de … Fixer la signification de chaque méta-donnée (multilingue). L'encyclopédie française bénéficie de la licence Wikipedia (GNU). [99][103] Aulus Cornelius Celsus (30 AD) described the linkage with alcohol, later onset in women and associated kidney problems: Again thick urine, the sediment from which is white, indicates that pain and disease are to be apprehended in the region of joints or viscera... Joint troubles in the hands and feet are very frequent and persistent, such as occur in cases of podagra and cheiragra. Le dictionnaire des synonymes est surtout dérivé du dictionnaire intégral (TID). [8][11], While it has been recommended that urate-lowering measures should be increased until serum uric acid levels are below 300–360 µmol/l (5.0–6.0 mg/dl),[60][57] there is little evidence to support this practice over simple putting people on a standard dose of allopurinol. loute (ma, min) : sexe masculin. Ma Loute, un film de Bruno Dumont : Roulotte de saltimbanque , maison . [8], Hyperuricemia is a classic feature of gout, but nearly half of the time gout occurs without hyperuricemia and most people with raised uric acid levels never develop gout. [8], Gouty tophi presenting as nodules on the finger and helix of the ear, Gout complicated by ruptured tophi, the exudite of which tested positive for uric acid crystals, Gout affects around 1–2% of the Western population at some point in their lifetimes and is becoming more common. [8] Treatment of associated health problems is also important. These seldom attack eunuchs or boys before coition with a woman, or women except those in whom the menses have become suppressed... some have obtained lifelong security by refraining from wine, mead and venery.[104]. Note also the soft tissue swelling at the lateral border of the foot. loute • Le Dictionnaire de la Zone, tout l'argot des banlieues. [109], A number of new medications are under study for treating gout, including anakinra, canakinumab, and rilonacept. Gout on X-rays of a left foot in the metatarsal-phalangeal joint of the big toe. terme utilisé pour désigner familièrement quelqu’un (cha va ma loute ?). Tough luck, Carlton. [8][19] Some 5.8 million people were affected in 2013. ... Extensive tophi may lead to chronic arthritis due to bone erosion. [22] Other triggers include physical trauma and surgery. [16] Microscopic tophi may be walled off by a ring of proteins, which blocks interaction of the crystals with cells and therefore avoids inflammation. [19] Rapid changes in uric acid may occur due to factors including trauma, surgery, chemotherapy and diuretics. © 2013-2020 Reverso Technologies Inc. All rights reserved. diminutif de "louloute", terme de tendresse à l'adresse d'un enfant, d'une jeune fille. [4] Other symptoms may rarely occur along with the joint pain, including fatigue and a high fever. [111] A recombinant uricase enzyme (rasburicase) is available but its use is limited, as it triggers an immune response. [10] It may also result in tophi, kidney stones, or kidney damage. | Privacy policy [81], NSAIDs are the usual first-line treatment for gout. [82] While indometacin has historically been the most commonly used NSAID, an alternative, such as ibuprofen, may be preferred due to its better side effect profile in the absence of superior effectiveness. These ancient manuscripts cite (now missing) Egyptian texts about gout that are claimed to have been written 1,000 years earlier by Imhotep. [24][25] Alcohol consumption is strongly associated with increased risk, with wine presenting somewhat less of a risk than beer or spirits. [108] The Tyrannosaurus rex specimen known as "Sue" is believed to have suffered from gout. Most communal societies have failed because of the lack of a good head. [10] Other joints, such as the heels, knees, wrists, and fingers, may also be affected. [38] When they break through the tophi, they trigger a local immune-mediated inflammatory reaction in macrophages, which is initiated by the NLRP3 inflammasome protein complex. [8] Under polarized light microscopy, they have a needle-like morphology and strong negative birefringence. Schwartz, Stephan A. In men over 30 and women over 50, rates are 2%. [68] Pegloticase is an option for the 3% of people who are intolerant to other medications. maflé (être) : repus voire mal à l’aise d’avoir trop mangé. Employé comme nom. It isn't a real drum that we hear today, it is the chimpanzee who has stopped breathing and is beating his chest. [4] An evolutionary loss of urate oxidase (uricase), which breaks down uric acid, in humans and higher primates has made this condition common. loute \lut\ féminin (Affectueux) Fille, jeune femme. [8][34] A body mass index greater than or equal to 35 increases male risk of gout threefold. Elapsed time: 137 ms. Word index: 1-300, 301-600, 601-900, More, Expression index: 1-400, 401-800, 801-1200, More, Phrase index: 1-400, 401-800, 801-1200, More. [69] It is a third line agent. Le service web Alexandria est motorisé par Memodata pour faciliter les recherches sur Ebay. vie communale définition. [61] If these medications are in chronic use at the time of an attack, it is recommended that they be continued. [10] Hyperuricemia is defined as a plasma urate level greater than 420 μmol/l (7.0 mg/dl) in males and 360 μmol/l (6.0 mg/dl) in females. [19], Febuxostat is only recommended in those who cannot tolerate allopurinol. Dans la région Picardie, on parle de « picard », alors qu’on emploie plutôt les sobriquets ch’ti, ch’timi dans le Nord-Pas-de-Calais ou encore rouchi dans la région de Valenciennes même si les gens du Nord parlent entre eux simplement de patois, une dénomination dépréciative. ©2020 Reverso-Softissimo. [36] Other medications that increase the risk include niacin, aspirin (acetylsalicylic acid), ACE inhibitors, angiotensin receptor blockers, beta blockers, ritonavir, and pyrazinamide.
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